Five-Day Rome Itinerary

The Perfect Itinerary for Food and Culture Lovers

The Roman Coloseum

Rome is where ancient history, stunning architecture, and world-class cuisine come together in a way that’s impossible to resist. Planning the perfect itinerary can feel overwhelming with so much to see and eat. That’s where I come in! 

Whether you’re a first-time visitor or a returning traveler looking for a deeper dive into the Eternal City, this five-day itinerary balances Rome’s must-see sights with incredible culinary experiences.

Cornetto pastries freshly baked and on a rack.

Day 1: Arrival & Iconic Landmarks

Morning: Start your Roman adventure with an espresso and cornetto at Sant’Eustachio Il Caffè, a legendary spot near the Pantheon. From here, explore:

  • Piazza Navona – One of Rome’s most beautiful squares, featuring Bernini’s Fountain of the Four Rivers.

  • The Pantheon – A masterpiece of ancient Roman engineering and home to Raphael’s tomb.

Lunch: Enjoy a classic Roman dish, such as cacio e pepe or carbonara, at Roscioli Salumeria con Cucina, a beloved deli restaurant among locals.

Afternoon: Stroll to the Trevi Fountain and toss in a coin for good luck. Then, walk to the Spanish Steps before indulging in gelato from Gelateria La Romana.

Dinner: Head to Armando al Pantheon, a historic trattoria serving traditional Roman cuisine with a refined touch.

The Roman parthenon interior dome

Day 2: Ancient Rome & Jewish Ghetto

Morning: Step back in time at the Colosseum, then explore the Roman Forum, the heart of ancient Rome.

Lunch: Walk over to the Jewish Ghetto, one of Rome’s most fascinating neighborhoods, for lunch at Ba’Ghetto or Nonna Betta, where you can try carciofi alla giudia (Jewish-style fried artichokes).

Afternoon: Visit the Portico of Octavia and stroll along the Tiber River.

Aperitivo: Before dinner, stop by Il Goccetto, a charming wine bar, for a glass of local wine.

Dinner: Dine at Trattoria Pennestri, a modern take on Roman cuisine featuring dishes like oxtail stew and handmade pasta.

Old stone bridge over the Tiber RIver

Day 3: Vatican City & Trastevere

Morning: Start with a visit to St. Peter’s Basilica, followed by the Vatican Museums and Sistine Chapel. (Book a skip-the-line ticket!)

Lunch: Visit Sorpasso, a stylish yet cozy spot near the Vatican, for a plate of tonnarelli cacio e pepe.

Afternoon: Cross the Tiber and wander through Trastevere, a charming, bohemian district filled with cobblestone streets and hidden gems.

Dinner: Experience Da Enzo al 29, a beloved trattoria serving hearty Roman classics. Be sure to try their burrata with anchovies and amatriciana.

Woodfire pizza

Day 4: Hidden Gems & Testaccio Food Tour

Morning: Visit Campo de’ Fiori, one of Rome’s best open-air markets, followed by a stop at the Palazzo Spada to see Borromini’s optical illusion gallery.

Lunch: Head to Testaccio, the city’s culinary heart, for a food tour exploring the best of Rome’s street food—supplì (fried rice balls), porchetta sandwiches, and maritozzo (sweet cream-filled buns). Testaccio Market is a must-visit!

Afternoon: Explore the Aventine Keyhole for a secret view of St. Peter’s Basilica, then relax at Giardino degli Aranci (Orange Garden), a quiet escape with stunning city views.

Dinner: Enjoy a leisurely meal at Per Me by Giulio Terrinoni, a Michelin-starred restaurant serving creative seafood dishes.

Day 5: Day Trip to Tivoli OR a Cooking Class

Option 1: Day Trip to Tivoli

Visit Villa d’Este, a UNESCO World Heritage Site known for its breathtaking fountains and gardens.

• Explore Villa Adriana, the vast Roman retreat of Emperor Hadrian.

• Enjoy lunch at Ristorante Sibilla, a historic restaurant with a terrace overlooking ancient ruins.

Option 2: Cooking Class in Rome

• Learn to make fresh pasta, tiramisu, or traditional Roman dishes with a local chef. Many classes include a market tour!

Enjoy the meal you prepared with a glass of Italian wine.

Final Aperitivo & Farewell Dinner:

• Toast your Roman adventure with an aperitivo at Hotel de Russie’s Stravinskij Bar or Salotto 42.

• For your last meal, go all out at La Pergola, Rome’s only three-Michelin-starred restaurant, or opt for a more relaxed, yet elegant, dinner at Rimessa Roscioli.

Final Tips for Your Rome Trip

  • Book major attractions in advance to avoid long lines.

  • Wear comfortable shoes—Rome’s cobblestone streets can be brutal.

  • Eat like a local—stick to trattorias and osterias instead of touristy spots.

  • Embrace the aperitivo culture—enjoy pre-dinner drinks and snacks to experience Rome like a Roman.

Rome is a city that never ceases to amaze, whether you’re visiting for the first time or the tenth. With this five-day itinerary, you’ll get a perfect balance of history, food, and local culture—ensuring that your time in the Eternal City is nothing short of unforgettable.

Where to Stay

ROME

The Hoxton Rome

Parquet floors, statement headboards, and brass lighting features throughout, while bold colors, local stones, and lacquered timbers nod to classic mid-century Italian design.

Six Senses Rome

Enjoy a serene and peaceful retreat that remains well-connected to celebrated monuments, with the Trevi Fountain, Pantheon, and Colosseum just an easy stroll away.

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